Pitt is fresh off a much-needed bye week, and it will be an important test on the road against Louisville to see if Pitt has made the adjustments necessary for a run to repeat as ACC Coastal champs — and ACC champs as a whole.
Pitt opened as a 1-point favorite against Louisville, and the over/under has been set at 56.5 points. The game will be played under the lights at Cardinal Stadium in Louisville, Kentucky Saturday at 8 p.m. The game will be broadcast on ACC Network.
DraftKings Sportsbook lists Pitt and Louisville as a pick’em, with both bets on either team holding -110 odds. There hasn’t been odds set for the over/under or Moneyline. FanDuel Sportsbook hasn’t set odds for the spread, over/under or Moneyline yet.
Louisville has experienced an up-and-down start to its own 2022 season, missing quarterback Malik Cunningham at times, with a 3-3 start — 1-3 in the ACC.
Aside from a Week 1 loss to a surprise Syracuse team, Louisville’s losses have come by four points against Syracuse and one point against Boston College. The Cards have picked up wins over USF, UCF and Virginia.
Pitt is 10-8 all-time against Louisville, dating back to a 27-6 win in the first meeting in 1976. It’s been a series of runs all-time. Pitt won the first four meetings, Louisville won the next seven meetings between 1990-2007 and Pitt has won six of the last seven.
Pitt won the most recent matchup 23-20 in 2020, a performance in which Kenny Pickett threw for 220 yards and two touchdowns and the defense forced three Cunningham interceptions.
The ACC Network broadcast crew will be announced at a later date.
